List of Famous people born in Santa Ana Department, El Salvador

Alfredo Alberto Pacheco was a Salvadoran footballer who had the record for most appearances on the El Salvador national football team when he was banned for life in 2013, for match-fixing while playing for the national team. He was murdered on December 27, 2015.

Francisco Guillermo Flores Pérez was a Salvadoran politician who served as President of El Salvador from June 1, 1999 to June 1, 2004 as a member of the conservative Nationalist Republican Alliance (ARENA). He previously served as a deputy of the Legislative Assembly from 1994 to 1999, having been president of the Assembly from 1997 to 1999.

José Napoleón Duarte Fuentes was a Salvadoran politician who served as President of El Salvador from June 1, 1984 to June 1, 1989. He was mayor of San Salvador before running for president in 1972. He lost, but the election is widely viewed as fraudulent. Following a counter-coup in 1979, Duarte led the subsequent civil-military Junta from 1980 to 1982. He was then elected president in 1984, defeating ARENA party leader Roberto D'Aubuisson.

Mercedes Gloria Salguero Gross was a Salvadoran politician, businesswoman, and one of the founders of the Nationalist Republican Alliance (ARENA). She served as the President of the Legislative Assembly of El Salvador from 1994 to 1997.

Joaquín Antonio Rivas Navarro is a Salvadoran professional footballer who plays for USL Championship club FC Tulsa.

Evelyn Yesenia García Marroquín is a Salvadoran cycle racer who rides for the Fenixs team. She is something of an all-rounder, having won time-trials and mountain stages in the past. She has won the Vuelta a El Salvador on two occasions, the only woman yet to do so, in 2004 and 2007. She was born in Santa Ana. García competed in the 2004 and 2008 Olympic Summer Games, both times in the road race and the 3000 m individual pursuit. She competed at the 2012 Summer Olympics in the Women's road race, finishing 26th.