List of Famous people born in Arica y Parinacota Region, Chile

Cristian Ignacio Garín Medone is a Chilean professional tennis player. He is the youngest Chilean player to win a high-level ATP match, defeating Dušan Lajović at just 16 years and 8 months old, in the first round of the 2013 VTR Open. He was the winner of the 2013 Junior French Open, beating Alexander Zverev in the final. In February 2020, he achieved a career high ATP singles ranking of 18.

Carolina Veronica Mestrovic Moroni is a Chilean singer, actress and TV host known for her role in TVN's Rojo fame contrafama, where she won the "singers category" in 2008.

Domingo Jhonny Vega Urzúa, commonly known as Américo, is a Chilean singer. He became known as the lead artist of Américo y la Nueva Alegría. He is the son of a locally known boleros singer, Melvin "Corazón" Américo. Americo was a coach on the second season of La Voz Ecuador in 2016.

Walter Orlando Ayoví Corozo is an Ecuadorian former professional footballer. He previously played as a left winger for Club Deportivo El Nacional in the Ecuadorian league and in the Ecuadorian national team, primarily in left defense. He is the cousin of fellow footballer Jaime Ayoví, who also plays in the Ecuadorian national team. He also holds Mexican citizenship.

Leo Quinteros is a Chilean singer-songwriter and guitarist. He made his official debut in 2004 with the album 1A, which was critically acclaimed for its technical finesse and lyrical depth.

Dante Eugenio Poli García is a Chilean football pundit and former player. He played as a defender.

Manuel García is a folk-pop Chilean singer-songwriter and guitarist. He has won several awards and has twice received the Chilean National Music Prize, awarded by the Chilean Government.

Denisse Astrid van Lamoen is a Chilean archer. In 2000, she became the first Chilean archer to compete at the Summer Olympics, but after failing a drug test in 2002 she left archery to study law. She later returned to the sport. In 2011, she was voted "Chile's Athlete of the Year" after winning at the 2011 World Archery Championships. She was selected to be Chile's flag-bearer at the 2012 Summer Olympics. She is of Dutch descent.